{"id":1064,"date":"2016-11-28T07:55:48","date_gmt":"2016-11-28T06:55:48","guid":{"rendered":"https:\/\/cegat.net\/web\/en\/?post_type=encyclopedia&amp;p=1064"},"modified":"2016-11-28T07:55:48","modified_gmt":"2016-11-28T06:55:48","slug":"first-trimester-screening","status":"publish","type":"encyclopedia","link":"https:\/\/www.cenata.de\/en\/encyclopedia\/first-trimester-screening\/","title":{"rendered":"First-trimester screening"},"content":{"rendered":"<p>A combination of a special ultrasound test (measuring <a href=\"https:\/\/www.cenata.de\/en\/encyclopedia\/nuchal-translucency\/\" target=\"_self\" title=\"An accumulation of fluid in the under the skin at the neck area of the unborn child that can be measured by ultrasound during first-trimester screening. A higher nuchal translucency may indicate the presence of chromosomal or other disorders of the unborn child.\" class=\"encyclopedia\">nuchal translucency<\/a> and possibly other factors such as nasal bone size) and a biochemical analysis of PAPP-A (Pregnancy-associated plasma protein A) and free &beta;-hCG (&szlig;-chain of the human chorionic gonadotropin) in the mother&rsquo;s blood serum. The test can be performed between weeks 11+0 and 14+0 of a pregnancy to determine the likelihood of <a href=\"https:\/\/www.cenata.de\/en\/encyclopedia\/fetal\/\" target=\"_self\" title=\"Relating to the unborn child\" class=\"encyclopedia\">fetal<\/a> chromosomal disorders (e.g. <a href=\"https:\/\/www.cenata.de\/en\/encyclopedia\/trisomy-21\/\" target=\"_self\" title=\"Trisomy 21 is the most common numerical chromosomal disorder in newborns. There are three copies of chromosome 21 and this leads to the development of Down syndrome.\" class=\"encyclopedia\">trisomy 21<\/a>).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A combination of a special ultrasound test (measuring nuchal translucency and possibly other factors such as nasal bone size) and a biochemical analysis of PAPP-A (Pregnancy-associated plasma protein A) and free \u03b2-hCG (\u00df-chain of the human chorionic gonadotropin) in the mother&#8217;s blood serum. The test can be performed between weeks 11+0 and 14+0 of a [&hellip;]<\/p>\n","protected":false},"author":1,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"class_list":["post-1064","encyclopedia","type-encyclopedia","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.cenata.de\/en\/wp-json\/wp\/v2\/encyclopedia\/1064","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cenata.de\/en\/wp-json\/wp\/v2\/encyclopedia"}],"about":[{"href":"https:\/\/www.cenata.de\/en\/wp-json\/wp\/v2\/types\/encyclopedia"}],"author":[{"embeddable":true,"href":"https:\/\/www.cenata.de\/en\/wp-json\/wp\/v2\/users\/1"}],"wp:attachment":[{"href":"https:\/\/www.cenata.de\/en\/wp-json\/wp\/v2\/media?parent=1064"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}