{"id":1036,"date":"2016-11-28T07:45:29","date_gmt":"2016-11-28T06:45:29","guid":{"rendered":"https:\/\/cegat.net\/web\/en\/?post_type=encyclopedia&amp;p=1036"},"modified":"2016-11-28T07:45:29","modified_gmt":"2016-11-28T06:45:29","slug":"structural-chromosomal-change","status":"publish","type":"encyclopedia","link":"https:\/\/www.cenata.de\/en\/encyclopedia\/structural-chromosomal-change\/","title":{"rendered":"Structural chromosomal change"},"content":{"rendered":"<p>A differentiation is made between structural and <a href=\"https:\/\/www.cenata.de\/en\/encyclopedia\/numerical-chromosomal-change\/\" target=\"_self\" title=\"Only a small percentage of chromosomal changes occur regularly. A distinction is made between numerical and structural chromosomal changes. With numerical chromosomal changes, a chromosome can be absent (monosomy), there can be an extra copy of a chromosome (trisomy) or multiple extra chromosomes (polyploidies).\" class=\"encyclopedia\">numerical chromosomal change<\/a>s. Structural chromosomal changes are divided into two categories: balanced and unbalanced.  Balanced chromosomal changes exist where part of a <a href=\"https:\/\/www.cenata.de\/en\/encyclopedia\/chromosome\/\" target=\"_self\" title=\"A chromosome is an complex of tightly-coiled DNA and the proteins which hold the structure together. Normal human cells contain 23 pairs of chromosomes - 22 autosomes and the X and Y sex chromosomes.\" class=\"encyclopedia\">chromosome<\/a> is relocated onto another. This shift in position does not normally affect the person with the change, but may affect their offspring. Unbalanced chromosomal disorders may involve the partial duplication or partial loss of some <a href=\"https:\/\/www.cenata.de\/en\/encyclopedia\/chromosome\/\" target=\"_self\" title=\"A chromosome is an complex of tightly-coiled DNA and the proteins which hold the structure together. Normal human cells contain 23 pairs of chromosomes - 22 autosomes and the X and Y sex chromosomes.\" class=\"encyclopedia\">chromosome<\/a> regions. The person with this change are usually directly affected.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A differentiation is made between structural and numerical chromosomal changes. Structural chromosomal changes are divided into two categories: balanced and unbalanced. Balanced chromosomal changes exist where part of a chromosome is relocated onto another. This shift in position does not normally affect the person with the change, but may affect their offspring. Unbalanced chromosomal disorders [&hellip;]<\/p>\n","protected":false},"author":1,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"class_list":["post-1036","encyclopedia","type-encyclopedia","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.cenata.de\/en\/wp-json\/wp\/v2\/encyclopedia\/1036","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cenata.de\/en\/wp-json\/wp\/v2\/encyclopedia"}],"about":[{"href":"https:\/\/www.cenata.de\/en\/wp-json\/wp\/v2\/types\/encyclopedia"}],"author":[{"embeddable":true,"href":"https:\/\/www.cenata.de\/en\/wp-json\/wp\/v2\/users\/1"}],"wp:attachment":[{"href":"https:\/\/www.cenata.de\/en\/wp-json\/wp\/v2\/media?parent=1036"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}